Emerging drugs for eosinophilic esophagitis

摘要: Introduction: Eosinophilic esophagitis (EoE) has emerged over the past two decades as an important esophageal disorder with significant associated morbidity. The prevalence of EoE now approximates that commonly recognized gastrointestinal diseases including inflammatory bowel disease. In adults, is a leading cause dysphagia and food impaction. Medications, elimination diets dilation are currently utilized for treatment EoE. While these approaches often effective, no pharmaceutical agents have yet been approved by Food Drug Administration (FDA). current medical therapies primarily consist topical corticosteroids adopted from formulations designed pulmonary delivery in patients asthma not optimized delivery. Areas covered: This article focuses on therapeutics being developed Several trials evaluated improved steroid vehicles to esophagus. No...