Renal arterial resistance index and computerized quantification of fibrosis as a combined predictive tool in chronic allograft nephropathy.

作者: Lars Pape , Michael Mengel , Gisela Offner , Michael Melter , Jochen H. H. Ehrich

DOI: 10.1111/J.1399-3046.2004.00229.X

关键词:

摘要: The renal arterial resistance index (RI) and the PicroSirius-Red stained cortical fractional interstitial fibrosis volume (VintFib) proved to be two independent methods that are reliable predictive factors of poor allograft outcome. No data have been published, which define correlation between ultrasound assessment quantitative morphologic changes. Renal biopsies were performed in 56 children according increases s-creatinine >10%. VintFib was calculated by computerized image analysis. RI determined segmental arteries, 1 yr after transplantation at time-point biopsy. RIs correlated significantly with time biopsy (r = 0.58, p 10%, mean 77 +/- 5 compared 69 6 patients 10%. For > 10% or 80 alone, it 87% 67%, respectively. combined measurement is a tool for risk developing long-term graft dysfunction kidney transplantation.

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