Efficacy of intravitreal conbercept injection in the treatment of retinopathy of prematurity.
作者： Yichen Bai , Huanjie Nie , Shiyu Wei , Xiaohe Lu , Xiaoyun Ke
DOI: 10.1136/BJOPHTHALMOL-2017-311662
关键词:
摘要: Background To evaluate the safety and efficacy of intravitreal conbercept (IVC) injection in treatment retinopathy prematurity (ROP). Methods Patients with ROP who underwent IVC injection Zhujiang Hospital from June 2015 to July 2016 were studied retrospectively. The primary outcome was defined as regression plus disease. secondary outcomes presence recurrence, number injections final Results A total 48 eyes 24 patients included. Among them, 9 5 had zone I ROP, 35 18 II 4 2 aggressive posterior ROP. mean gestational age 28.5±1.6 weeks, birth weight 1209.6±228.6 g, postmenstrual first injection 34.2±1.9 weeks follow-up period 31.0±4.7 weeks. Forty (83.3%) received IVC only once, disease occurred at an average 3.5±1.5 after conbercept. For eight recurrent (16.7%), four a second IVC and remaining laser photocoagulation, 3 No lens opacity, vitreous haemorrhage, entophthalmia or retinal detachment observed during follow-up. Conclusion is effective for
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