Postoperative infection and mortality following elective surgery in the International Surgical Outcomes Study (ISOS)

摘要: BACKGROUND Postoperative infection is one of the most frequent and important complications after surgery. The epidemiology following elective surgery remains poorly described. METHODS This was a prospective analysis International Surgical Outcomes Study (ISOS) describing by 30 days Associations between postoperative (primary outcome) baseline demographic, surgical, anaesthetic risk factors were assessed. Analyses carried out using logistic linear regression models. Secondary outcomes 30-day mortality duration hospital stay. Treatments received patients different types evaluated. RESULTS Some 44 814 included in analysis, with total 4032 infections occurring 2927 (6.5 per cent). Overall, 206 died, whom 99 (3.4 cent) had infection. 737 (18.3 severe; superficial surgical-site (1320, 32.7 cent), pneumonia (708, 17.6 urinary tract (681, 16.9 Excluding missing data, antimicrobials used 2126 2749 (77.3 522 2164 (24.1 required admission to critical care. Factors associated an increased incidence adjusted analyses were: age, male sex, ASA grade, co-morbid disease, preoperative anaemia, technique, surgical category, severity, cancer Infection significantly death (odds ratio 4.68, 95 cent c.i. 3.39 6.47; P < 0.001), stay on average 6.45 (6.23 6.66) (P < 0.001). CONCLUSION common complication Recognition modifiable will help inform appropriate prevention strategies.