Sensor device for target particles in a sample
作者： Jeroen Veen , Josephus Arnoldus Henricus Maria Kahlman , Bart Michiel De Boer , Coen Adrianus Johannes Verschuren , Mischa Megens
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摘要: The invention relates to a sensor device(100) and method for the determination of amount target particles(1) at contact surface(112) adjacent sample chamber(2). Target in chamber are detected by element(SE) least one corresponding sensor-signal (s, s') is provided. An evaluation unit(EU) then determines first zone(Z1) immediately contracts second zone(Z2) distance(z) away from surface based on this sensor-signal. In an optical measurement approach, frustrated total internal reflection taking place under different operating conditions (e.g. wavelength, angle incidenceq) may be used extract information about zones(Z1, Z2). magnetic excitation fields excite particles differently inthe zone(Z2). Moreover, temporalcourse sensor-signal(s, can evaluated, particularly with respect stochastic movements ofthe particles(1).
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