Phosphine-mediated synthesis of trifluoromethyl substituted pyrroles using TFAA as the CF3 source
作者： Dan-Dan Tang , Yao Wang , Jun-Ru Wang , Peng-Fei Xu
DOI: 10.1016/J.TETLET.2014.05.127
关键词:
摘要: A phosphine-mediated synthesis of trifluoromethyl substituted pyrrole derivatives was achieved. The method described here is very fast, operationally simple, and easily amenable to scale-up, commercially available trifluoroacetic anhydride (TFAA) used as the only source. wide range products were obtained with good yields under mild condition using this method. 0(C)2014 Elsevier Ltd. All rights reserved.
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