Effect of stretch and contraction on caveolae of smooth muscle cells.

摘要: The number of caveolae present at the surface smooth muscle cells guinea-pig taenia coli and visualized by freeze-fracture is about 35 per micron2. (By comparison, endothelial intramuscular capillaries have 73 micron2). packing density not significantly different in strips isotonically contracted with carbachol or stretched relaxed a calcium-free solution, under range loads varying from 1 to 15 g. Also diameter fractured necks appears unchanged all experimental conditions tested. plasma membrane often shows ring intramembranous particles rimming opening caveola; on other hand, are rare themselves. close relation between sarcoplasmic reticulum readily preparations. Characteristic changes cell shape accompany contraction relaxation muscle. On occasions small aggregates found it possible that they represent punctate gap junctions. However, characteristic clusters circular musculature caecum ileum seen coli.