Electrochemical biocomputing: a new class of molecular-electronic logic devices

摘要: Biocomputing, a subarea of unconventional chemical computing, is performed by DNA, protein/enzymes, and other living organisms. Recently, various biomolecular logic gates employing optical changes or PAGE measurements have been studied intensively using inputs. However, the low detection speed, which an inherent characteristic method, has prevented it from being developed technologically. Most reported to date are mainly based on fluorescence, phosphorescence, colorimetric outputs, laborious, time-consuming, unsuitable for directly detecting subtle structures. They also suffer limitations cumbersomely interfacing outputs with nonmolecular-based technologies. In this context, assisted electrochemistry one most popular techniques due combined advantages high sensitivity, specificity, small volume requirements, cost, possibility mass production via microelectronic industry. addition, necessary that future molecular elements strongly related successful linkage molecules onto conductive semiconductive support. highlight, we will focus bioelectronic computing devices enzymes, biofuel cells.