Toxicité cutanée des anti-EGFR (epidermal growth factor receptor) : algorithme thérapeutique du groupe français PROCUR

摘要: The epidermal growth factor receptors (EGFR)-inhibitors are frequently responsible for cutaneous adverse drug reactions that may alter the patients' quality of life and hamper continuation treatment. We present here experience a group French multidisciplinary experts - PROCUR (PRise en charge de la tOxicite CUtanee des anti-EGFR) created in order to establish therapeutic algorithm. It was built three steps under responsibility steering committee: (1) systematic literature review performed by dermatologists one oncologist; (2) regional meetings evaluated practical aspect treatments France; (3) final meeting confrontating practices France evidence-based medicine including committee, bibliographic group, oncologists, radiotherapists, hepato-gastroenterologists involved scientific committees, resulted algorithm, resulting collegial writing this This study should facilitate standardised, optimised management skin toxicity associated with EGFR-inhibitors.