Cutaneous adverse effects with HER1/EGFR-targeted agents: is there a silver lining?

作者: Román Peréz-Soler , Leonard Saltz

DOI: 10.1200/JCO.2005.00.6916

关键词: OncologyCetuximabSurvival analysisEpidermal growth factor receptorImmunologyGefitinibErlotinibSurrogate endpointInternal medicineMedicineRashAdverse effect

摘要: The human epidermal growth factor receptor (HER1/EGFR) is dysregulated in many solid tumors, making it an attractive target for anticancer therapy. A number of agents that target this …

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