Biomarkers in the Overactive Bladder Syndrome

摘要: Overactive bladder (OAB) is a symptomatic complex affecting both men and women. The overall incidence above 10% but may exceed 40% in the elderly population (Irwin et al., 2006; Irwin 2009; Sexton 2009a). OAB defined by International Continence Society (ICS) as clinical syndrome characterized urinary urgency, with or without incontinence, usually frequency nocturia (Abrams 2002, 2003; Hashim & Abrams, 2007). Urgency, which storage symptom sudden compelling desire to pass urine difficult defer, hallmark it only one that must be present order establish diagnosis of 2003). Several comorbidities are very common among patients, including depression, insomnia fractures (Coyne 2008; 2009a; 2009b). economic costs OAB, associated medical consultations, therapy diminished productivity at work, reach billions dollars 2009) will certainly increase demographic shift an ageing population.