Telemetry in a motion‐sickness model implicates the abdominal vagus in motion‐induced gastric dysrhythmia

作者: Nathalie Percie du Sert , Kit M. Chu , Man K. Wai , John A. Rudd , Paul L. R. Andrews

DOI: 10.1113/EXPPHYSIOL.2009.052001

关键词:

摘要: In humans, motion sickness is associated with disruption of normal gastric myoelectric activity, and it has been proposed that this results from an imbalance autonomic nervous system activity. We used the established Suncus murinus (house musk shrew) model motion-induced emesis to investigate effect horizontal on activity (recorded using telemetry) involvement abdominal vagi. Surgical vagotomy increased baseline dysrhythmia reduced dominant power signals. response motion, was in sham-operated animals but not vagotomized animals. Vagotomy, however, failed affect emesis. conclusion, had a differential animals, which consistent hypothesis arises imbalance.

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