Postoperative prophylactic anticonvulsant therapy in cerebral gliomas.

摘要: Abstract A retrospective study was performed to evaluate the efficacy of prophylactic anticonvulsants in preventing seizures 68 patients with supratentorial astrocytomas who had been treated operation and irradiation no previous history convulsions. Thirty-three received 38 did not. The incidence all types (generalized convulsions or partial) lower receiving anticonvulsants. No an impairment consciousness occurred documented therapeutic anticonvulsant blood levels. overall 39% untreated 21% patients. major including tonic/clonic partial complex zero levels 18% Regarding both groups, there tend be fewer older patients, females, a higher grade malignancy, more radical resection tumor. This suggests that are frequent occurrence after for glioma may effective reducing those seizures.