Screening for multidrug-resistant bacteria as a predictive test for subsequent onset of nosocomial infection.

摘要: Objective. To investigate whether carriage of multidrug-resistant bacteria is a risk factor for nosocomial infection and detection predictive subsequent onset infection. Methods. In this observational cohort (study period, June 1998 through October 2002), nasal rectal swab specimens from 412 consecutive patients admitted to the intensive care unit were tested bacteria. Concomitantly, responsible any infection, date some known clinical factors noted. These adjusted potential confounders, using Cox model stratified on propensity score carriage. The diagnostic characteristics test, including positive negative likelihood ratios, calculated all strata score. Results. Forty-two carrying Nosocomial occurred in 95 patients, whom 16 (38%) carriers, 79 (83%) noncarriers (P = .01). After adjustment statistical analysis revealed that remained (relative risk, 2.08 [95% confidence interval {CI}, 1.13-3.81]). Receipt antibiotic treatment at time admission was found be protective against A result test seemed an efficient predictor (positive ratio, 2.05 CI, 1.15-3.66]), although not (negative 0.91 0.73-1.11]). Conclusion. Carriage proved However, useful as tool only with result.