Estimating the urinary sodium excretion in patients with chronic kidney disease is not useful in monitoring the effects of a low-salt diet.

摘要: Background Several epidemiologic studies have suggested that the urine sodium excretion (USE) can be estimated in lieu of performing 24-hour collection. However, this method has not been verified patients with chronic kidney disease (CKD) or an interventional study. The purpose study was to evaluate usefulness estimating USE a prospective low-salt diet education cohort (ESPECIAL). Methods A new formula developed on basis morning fasting samples from 228 CKD ESPECIAL cohort. This compared previous four formulas prediction after treatment olmesartan and education. Results Most previously reported had low predictability measured based Only Tanaka showed small but significant bias (9.8 mEq/day, P < 0.05) correlation (r = 0.34). In contrast, improved (-0.1 mEq/day) 0.569) at baseline. demonstrated no (-1.2 same 0.571) 8 weeks olmesartan. Intensive elicited decrease USE. none predicted change adjustment. Conclusion We more reliable for patients. Although is applicable study, it may unsuitable individual intake intervention