Association of the Estimated 24-H Urinary Sodium Excretion with Albuminuria in Adult Koreans: The 2011 Korea National Health and Nutrition Examination Survey

作者: Sang Youb Han , Jae Won Hong , Jung Hyun Noh , Dong-Jun Kim

DOI: 10.1371/JOURNAL.PONE.0109073

关键词: EndocrinologySalt intakeMicroalbuminuriaExcretionBody mass indexPhysiologyQuartileMedicineInternal medicineNational Health and Nutrition Examination SurveyOdds ratioAlbuminuria

摘要: Background Sodium intake and albuminuria have important roles in blood pressure renal progression. Although their relationship has been reported, the results not consistent all studies examined small populations. Objective This study investigated role of estimated 24-h urinary sodium excretion as a marker albuminuria. Design investigation included 5,187 individuals age 19 years older from cross-sectional, nationally representative, stratified survey: The Korea National Health Nutrition Examination Survey (KNHANES V-2), 2011. Albuminuria was defined albumin/creatinine ratio ≥30 mg/g. spot urine. Results On classifying our participants into quartiles based on excretion, prevalence increased with (5.3, 5.7, 7.5, 11.8% first through fourth quartiles, respectively, p for trend <0.001). Even after adjusting age, sex, diabetes, obesity, hypertension, significance persisted. In multiple logistic regression analysis, second third were associated presence quartile control. However, significantly (odds 1.61 [95% confidence interval 1.71–2.21], = 0.003) hypertension. Conclusions These findings suggest that salt is general Korean adult population.

参考文章(31)
CS Fox, MG Larson, S-J Hwang, EP Leip, N Rifai, D Levy, EJ Benjamin, JM Murabito, JB Meigs, RS Vasan, None, Cross-sectional relations of serum aldosterone and urine sodium excretion to urinary albumin excretion in a community-based sample. Kidney International. ,vol. 69, pp. 2064- 2069 ,(2006) , 10.1038/SJ.KI.5000378
Enyu Imai, Yoshinari Yasuda, Masaru Horio, Kanako Shibata, Sawako Kato, Yu Mizutani, Junko Imai, Mutsuharu Hayashi, Hideki Kamiya, Yutaka Oiso, Toyoaki Murohara, Shoichi Maruyama, Seiichi Matsuo, Validation of the equations for estimating daily sodium excretion from spot urine in patients with chronic kidney disease Clinical and Experimental Nephrology. ,vol. 15, pp. 861- 867 ,(2011) , 10.1007/S10157-011-0523-0
Kristal J Aaron, Ruth C Campbell, Suzanne E Judd, Paul W Sanders, Paul Muntner, Association of dietary sodium and potassium intakes with albuminuria in normal-weight, overweight, and obese participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study The American Journal of Clinical Nutrition. ,vol. 94, pp. 1071- 1078 ,(2011) , 10.3945/AJCN.111.013094
Jong Chul Won, Yun Jeong Lee, Jung Min Kim, Sang Youb Han, Jung Hyun Noh, Kyung Soo Ko, Byoung Doo Rhee, Dong-Jun Kim, Prevalence of and Factors Associated with Albuminuria in the Korean Adult Population: The 2011 Korea National Health and Nutrition Examination Survey PLoS ONE. ,vol. 8, pp. e83273- ,(2013) , 10.1371/JOURNAL.PONE.0083273
Junko TAMAKI, Yuriko KIKUCHI, Katsushi YOSHITA, Toru TAKEBAYASHI, Nagako CHIBA, Taichiro TANAKA, Tomonori OKAMURA, Fumiyoshi KASAGI, Junko MINAI, Hirotsugu UESHIMA, HIPOP-OHP Research Group, Stages of change for salt intake and urinary salt excretion: baseline results from the High-Risk and Population Strategy for Occupational Health Promotion (HIPOP-OHP) study. Hypertension Research. ,vol. 27, pp. 157- 166 ,(2004) , 10.1291/HYPRES.27.157
M. Vedovato, G. Lepore, A. Coracina, A. R. Dodesini, E. Jori, A. Tiengo, S. Del Prato, R. Trevisan, Effect of sodium intake on blood pressure and albuminuria in Type 2 diabetic patients: the role of insulin resistance. Diabetologia. ,vol. 47, pp. 300- 303 ,(2004) , 10.1007/S00125-003-1303-5
T. Konta, Z. Hao, H. Abiko, M. Ishikawa, T. Takahashi, A. Ikeda, K. Ichikawa, S. Takasaki, I. Kubota, Prevalence and risk factor analysis of microalbuminuria in Japanese general population: the Takahata study. Kidney International. ,vol. 70, pp. 751- 756 ,(2006) , 10.1038/SJ.KI.5001504
Henry C. M. Yu, Louise M. Burrell, M. Jane Black, Leonard L. Wu, Rodney J. Dilley, Mark E. Cooper, Colin I. Johnston, Salt Induces Myocardial and Renal Fibrosis in Normotensive and Hypertensive Rats Circulation. ,vol. 98, pp. 2621- 2628 ,(1998) , 10.1161/01.CIR.98.23.2621
Charlotte Jones-Burton, Shiraz I. Mishra, Jeffrey C. Fink, Jeanine Brown, Weyinshet Gossa, George L. Bakris, Matthew R. Weir, An In-Depth Review of the Evidence Linking Dietary Salt Intake and Progression of Chronic Kidney Disease American Journal of Nephrology. ,vol. 26, pp. 268- 275 ,(2006) , 10.1159/000093833
H A Koomans, J C Roos, E J Dorhout Mees, I M Delawi, Sodium balance in renal failure. A comparison of patients with normal subjects under extremes of sodium intake. Hypertension. ,vol. 7, pp. 714- 721 ,(1985) , 10.1161/01.HYP.7.5.714