作者: Sang Youb Han , Jae Won Hong , Jung Hyun Noh , Dong-Jun Kim
DOI: 10.1371/JOURNAL.PONE.0109073
关键词: Endocrinology 、 Salt intake 、 Microalbuminuria 、 Excretion 、 Body mass index 、 Physiology 、 Quartile 、 Medicine 、 Internal medicine 、 National Health and Nutrition Examination Survey 、 Odds ratio 、 Albuminuria
摘要: Background Sodium intake and albuminuria have important roles in blood pressure renal progression. Although their relationship has been reported, the results not consistent all studies examined small populations. Objective This study investigated role of estimated 24-h urinary sodium excretion as a marker albuminuria. Design investigation included 5,187 individuals age 19 years older from cross-sectional, nationally representative, stratified survey: The Korea National Health Nutrition Examination Survey (KNHANES V-2), 2011. Albuminuria was defined albumin/creatinine ratio ≥30 mg/g. spot urine. Results On classifying our participants into quartiles based on excretion, prevalence increased with (5.3, 5.7, 7.5, 11.8% first through fourth quartiles, respectively, p for trend <0.001). Even after adjusting age, sex, diabetes, obesity, hypertension, significance persisted. In multiple logistic regression analysis, second third were associated presence quartile control. However, significantly (odds 1.61 [95% confidence interval 1.71–2.21], = 0.003) hypertension. Conclusions These findings suggest that salt is general Korean adult population.