Potentiation of antitumor effect of bleomycin by local electric pulses in mouse bladder tumor.

作者: OSAMU YAMAGUCHI , CHIHARU IRISAWA , KEIICHI BABA , MASAHIKO OGIHARA , TAKASHI YOKOTA

DOI: 10.1620/TJEM.172.291

关键词:

摘要: C3H mice bearing subcutaneously transplanted mouse bladder carcinoma (MBT-2) were treated with intramuscular injection of bleomycin followed by local delivery electric pulses at the tumor site. The tumors markedly reduced and even disappeared for several days after this treatment. Neither nor administration alone showed a significant inhibitory effect on growth. Thus, it is demonstrated that in antitumor can be considerably potentiated pulses.

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