Elevated maternal serum α-fetoprotein levels and oligohydramnios: Poor prognosis for pregnancy outcome

摘要: The outcome of 21 pregnancies with elevated maternal serum α-fetoprotein levels associated oligohydramnios was studied. Seven the ended in spontaneous abortion or intrauterine fetal death before week 24 pregnancy. Five patients experienced premature labor between and 26 weeks gestation; each fetus either stillborn died immediate neonatal period. Four were delivered infants after 32 infant electively had their terminated. One patient at term a healthy, growth retarded male who on follow-up age 17 months developmentally normal. Only three cases defect. Patients should be counseled that, even absence demonstrable cause for diminished amniotic fluid ultrasonography, raised coupled seem to carry poor prognosis.