Sleep Duration and Snoring in Relation to Biomarkers of Cardiovascular Disease Risk Among Women With Type 2 Diabetes
作者： C. J. Williams , F. B. Hu , S. R. Patel , C. S. Mantzoros
DOI: 10.2337/DC06-2107
关键词:
摘要: OBJECTIVE —Sleep habits have been associated with risk of cardiovascular disease (CVD) and metabolic disturbances, but the mechanisms underlying these associations yet to be fully elucidated. We aim determine whether sleep duration and/or snoring are biomarkers CVD in women type 2 diabetes. RESEARCH DESIGN AND METHODS —We studied 935 aged 43–69 years enrolled Nurses’ Health Study cohort diabetes who had no history documented coronary heart or stroke 1990. Information on frequency was collected 1986 from mailed questionnaires, were measured blood samples taken 1989–1990. RESULTS —Longer increased levels C-reactive protein after adjusting for age, BMI, lifestyle factors, family diabetes, glycemic control, medication use ( P = 0.05). HDL decreased short long among normotensive 0.02) not hypertensive women. More frequent directly triglycerides inversely cholesterol (0.03) adiponectin 0.03) multivariate-adjusted analyses. CONCLUSIONS —The lipid profile, hormone measures, inflammatory markers may partially explain previously reported relationship between disorders.
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Daniel J. Gottlieb, Susan Redline, F. Javier Nieto, Carol M. Baldwin, Anne B. Newman, Helaine E. Resnick, Naresh M. Punjabi, Association of Usual Sleep Duration With Hypertension: The Sleep Heart Health Study Sleep. ,vol. 29, pp. 1009- 1014 ,(2006) , 10.1093/SLEEP/29.8.1009
J Hedner, L Sjöström, K Stenlöf, R R Grunstein, Impact of obstructive sleep apnea and sleepiness on metabolic and cardiovascular risk factors in the Swedish Obese Subjects (SOS) Study International Journal of Obesity. ,vol. 19, pp. 410- 418 ,(1995)
Eijiro Ohga, Takahide Nagase, Tetsuji Tomita, Shinji Teramoto, Takeshi Matsuse, Hirofumi Katayama, Yasuyoshi Ouchi, Increased levels of circulating ICAM-1, VCAM-1, and L-selectin in obstructive sleep apnea syndrome Journal of Applied Physiology. ,vol. 87, pp. 10- 14 ,(1999) , 10.1152/JAPPL.1999.87.1.10
A. N. Vgontzas, E. Zoumakis, E. O. Bixler, H.-M. Lin, H. Follett, A. Kales, G. P. Chrousos, Adverse Effects of Modest Sleep Restriction on Sleepiness, Performance, and Inflammatory Cytokines The Journal of Clinical Endocrinology and Metabolism. ,vol. 89, pp. 2119- 2126 ,(2004) , 10.1210/JC.2003-031562
Timothy H. Monk, Daniel J. Buysse, Lynda R. Rose, J'aime A. Hall, David J. Kupfer, THE SLEEP OF HEALTHY PEOPLE—A DIARY STUDY Chronobiology International. ,vol. 17, pp. 49- 60 ,(2000) , 10.1081/CBI-100101031
Dimitris A. Papanicolaou, Edward O. Bixler, Anthony Kales, Kathy Tyson, George P. Chrousos, Alexandros N. Vgontzas, Elevation of Plasma Cytokines in Disorders of Excessive Daytime Sleepiness: Role of Sleep Disturbance and Obesity The Journal of Clinical Endocrinology & Metabolism. ,vol. 82, pp. 1313- 1316 ,(1997) , 10.1210/JCEM.82.5.3950
Takuya Yokoe, Kenji Minoguchi, Hirofumi Matsuo, Naruhito Oda, Hideko Minoguchi, Gen Yoshino, Tsutomu Hirano, Mitsuru Adachi, Elevated Levels of C-Reactive Protein and Interleukin-6 in Patients With Obstructive Sleep Apnea Syndrome Are Decreased by Nasal Continuous Positive Airway Pressure Circulation. ,vol. 107, pp. 1129- 1134 ,(2003) , 10.1161/01.CIR.0000052627.99976.18
Frank B. Hu, Walter C. Willett, Tricia Li, Meir J. Stampfer, Graham A. Colditz, JoAnn E. Manson, Adiposity as Compared With Physical Activity in Predicting Mortality Among Women Obstetrical & Gynecological Survey. ,vol. 60, pp. 311- 312 ,(2005) , 10.1097/01.OGX.0000160575.50215.93
Naresh M Punjabi, Murtuza M Ahmed, Vsevolod Y Polotsky, Brock A Beamer, Christopher P O'Donnell, None, Sleep-disordered breathing, glucose intolerance, and insulin resistance Respiratory Physiology & Neurobiology. ,vol. 136, pp. 167- 178 ,(2003) , 10.1016/S1569-9048(03)00079-X
Robert Wolk, Anna Svatikova, Christy A. Nelson, Apoor S. Gami, Kogilan Govender, Mikolaj Winnicki, Virend K. Somers, Plasma Levels of Adiponectin, a Novel Adipocyte‐Derived Hormone, in Sleep Apnea Obesity Research. ,vol. 13, pp. 186- 190 ,(2005) , 10.1038/OBY.2005.24