Health-related quality of life is compromised in individuals with spina bifida: results from qualitative and quantitative studies

摘要: Spina bifida (SB) accounts for approximately 90% of total neural tube defects. According to the degree SB severity, range associated symptoms and complications varies greatly. Given complexity diversity these complications, individuals with might suffer from livelong impairment. This review presents an overview impact on patients' health-related quality life (HRQoL) explores results published quantitative qualitative studies regarding HRQoL patients, as well comparing existing national norms. A literature search using three electronic databases PUBMED, PsycINFO, Embase was performed identify relevant dating January 1976 November 2010. To satisfy initial inclusion criteria, articles had contain that were specific in patients SB. Findings highlight is significantly impaired Making sure public aware disease how minimise risk NTD, such (e.g., through adequate folate levels at time conception, etc.) essential ensure fewer face burden NTDs future.