Childhood-Onset Schizophrenia: History of the Concept and Recent Studies

摘要: Schizophrenic disorders in childhood are rare: 0.1-1 percent of all schizophrenic manifest themselves before age 10, and 4 15. There is, however, a remarkable increase schizophrenia during adolescence. Age developmental stage also influence symptoms, course, outcome. The evidence for male preponderance the very early-onset group (< 14) does not apply adolescents over 14. presence positive negative precursor symptoms can be demonstrated child adolescent first clinical manifestation leading to inpatient treatment. With regard pharmacologic treatment, atypical neuroleptics such as clozapine used successfully. As outcome, psychoses with early have poor prognosis. patients' premorbid personality seems great importance: A prognosis found patients who were cognitively impaired, shy, introverted, withdrawn beginning their psychotic state.