Impact of hematological diagnosis on early and late outcome after laparoscopic splenectomyrid

摘要: Background: Laparoscopic splenectomy (LS) is now regarded as the treatment of choice for autoimmune thrombopenia (ITP). However, there have been few reports describing application LS to other splenic diseases, such malignant entities and conditions associated with splenomegaly. Hematological diseases specific clinical features that can influence immediate outcome after LS. Although long-term effects are unknown, a risk splenosis has suggested. Therefore, we designed study analyze impact primary hematological disease on late in prospective series patients. Methods: We performed analysis 111 done between February 1993 March 1999. The patients were classified by indications into following four groups: (a) group 1, low platelet count. This was further subdivided 1A, idiopathic thrombocytopenic purpura (ITP) (n= 48) 1B, HIV-related ITP 8); (b) 2, anemia. 2A, hemolytic anemia 8), 2B, spherocytosis 11); (c) 3, malignancy 28); (d) 4, others 8). Immediate outcomes recorded prospectively. status complications reviewed mean follow-up 24 ± 18 months. Results: There no significant differences groups terms conversion, transfusion requirements, morbidity, although morbidity slightly higher 3. hospital stay significantly longer 3 4 than 1 2. Long-term showed satisfactory results ≥75% (group 82%; 88%; 100%; 75%; 88%). Overall, 8.3% mortality 6.2%, mainly due deaths (six 22 patients). Conclusion: safe reproducible procedure most indications, similar benign response comparable standard observed open series.