The relative protective effects of moderate dietary restriction versus dietary modification on spontaneous cardiomyopathy in male Sprague-Dawley rats.
作者： Masayuki Kemi , Kevin P. Keenan , Carol Mccoy , Chao-Min Hoe , Keith A. Soper
DOI: 10.1177/019262330002800208
关键词:
摘要: The relative protective effects of modifying dietary protein, fat, fiber, and energy content vs moderate food or restriction (DR) on spontaneous cardiomyopathy Charles River male Sprague-Dawley (SD) rats was evaluated at 1 2 years. For years, SD were fed Purina Rodent Chow 5002 (21.4% 5.7% 4.1% 3.1 kcal/g) a modified rodent chow 5002-9 (13.6% 4.6% 15.7% crude 2.4 ad libitum (AL) by DR approximately 65% the caloric intake AL group diet. Serum lipids, carcass composition, organ weights hearts qualitatively quantitatively examined microscopically for Cardiomyopathy characterized colocalization myocardial degeneration, development subepicardial, perivascular, subendocardial, interstitial fibrosis, mononuclear inflammatory cell infiltration that increased incidence severity in an age-dependent manner f...
sagepub.com
cabdirect.org
sci-hub.se 参考文章(59)
E. J. Masoro, Physiological Consequences of Dietary Restriction: An Overview Springer, Berlin, Heidelberg. pp. 115- 122 ,(1991) , 10.1007/978-3-642-58181-6_11
M M Klinger, C N Boozer, G D MacCarter, Body weight and composition in the Sprague Dawley rat: comparison of three outbred sources. Laboratory Animal Science. ,vol. 46, pp. 67- 70 ,(1996)
Richard T. Robertson, Ronald W. Hart, David A. Neumann, Dietary restriction : implications for the design and interpretation of toxicity and carcinogenicity studies ILSI Press. ,(1995)
Biological effects of dietary restriction Springer Berlin Heidelberg. ,(1991) , 10.1007/978-3-642-58181-6
David L. Snyder, Jay Roberts, Eitan Friedman, Handbook of pharmacology of aging CRC Press. ,(1996)
Arne D. Peterson, B. R. Baumgardt, Influence of Level of Energy Demand on the Ability of Rats to Compensate for Diet Dilution The Journal of Nutrition. ,vol. 101, pp. 1069- 1074 ,(1971) , 10.1093/JN/101.8.1069
Roy L. Walford, Richard. Weindruch, The Retardation of Aging and Disease by Dietary Restriction ,(1988)
Caleb Ellicott Finch, Longevity, senescence, and the genome ,(1990)
Kevin P. Keenan, Gordon C. Ballam, Rakesh Dixit, Keith A. Soper, Philippe Laroque, Britta A. Mattson, Stephen P. Adams, John B. Coleman, The Effects of Diet, Overfeeding and Moderate Dietary Restriction on Sprague-Dawley Rat Survival, Disease and Toxicology Journal of Nutrition. ,vol. 127, ,(1997) , 10.1093/JN/127.5.851S
Arne D. Peterson, B. R. Baumgardt, Food and Energy Intake of Rats Fed Diets Varying in Energy Concentration and Density The Journal of Nutrition. ,vol. 101, pp. 1057- 1067 ,(1971) , 10.1093/JN/101.8.1057