Serotonin immunoreactivity in pancreatic endocrine neoplasms (carcinoid tumors).

摘要: Primary serotonin secreting pancreatic endocrine neoplasms (carcinoid tumors) are extremely rare and may be associated with manifestations of the carcinoid syndrome. Two cases primary tumor pancreas liver metastases showed clinical biochemical features Both demonstrated strong positive immunoreactivity for within cells. In an attempt to determine relationship between tumors other neoplasms, immunostains were performed on 11 additional islet cell non-neoplastic tissues. These (36%). addition, focal staining was present in ducts ductules (88%), acini (22%), islets Langerhans (33%). Based these observations, specific criteria suggested diagnosis tumor.