Durable Response of Metastatic Squamous Cell Carcinoma of the Skin to Ipilimumab Immunotherapy.

作者: Fiona Day , Mahesh Kumar , Linda Fenton , Craig Gedye

DOI: 10.1097/CJI.0000000000000146

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摘要: A 72-year-old male patient was receiving second-line chemotherapy for metastatic squamous cell carcinoma of the skin (SCCS) when he diagnosed with concurrent melanoma (BRAF mutant). Chemotherapy ceased and treated 4 cycles ipilimumab immunotherapy. The experienced clinical benefit durable remission in both malignancies remains free cancer progression 8 months after last cycle ipilimumab. Response SCCS to has not been previously described, however this case recent reports pembrolizumab efficacy confirm critical role immune system pathogenesis suggest further exploration checkpoint immunotherapy treatment disease.

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