Does granulosa cell apoptosis have a role in the etiology of unexplained infertility?
作者： Mehmet İdil , İsmail Çepni , Gülten Demirsoy , Pelin Öcal , Funda Salihoğlu
DOI: 10.1016/S0301-2115(03)00365-8
关键词:
摘要: Abstract Objective ( s ): To compare granulosa cell apoptosis in patients with unexplained infertility and tubal factor. Accelerated may be the cause of infertility. Study design : Setting was IVF-ET Unit Cerrahpasa Medical Faculty, Istanbul University. GnRH analogs gonadotropins were used for ovulation induction n =15) factor undergoing vitro fertilization embryo transfer (IVF-ET) procedures. Following HCG injection follicular aspiration, cells assessed using situ DNA nick end labelling method rate further determined by flow cytometry. Apoptosis rates compared between two groups. Mann–Whitney’s U -test Student’s t statistics. Results significantly higher group (33.20±35.62% versus 10.10±17.23%). Conclusion Granulosa seems to have a role etiology
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