HYPOGLYCEMIC ACTIVITY OF COPERNICIACERIFERA MART.L.EAF POWDER EXTRACT IN THE TREATMENT OF ALLOXAN-INDUCED DIABETIC MICE
作者： MÁrcia Maria Mendes Marques , Isaac Neto Goes Da Silva , Paula Alves Salmito Rodrigues , Izabel Florindo Guedes , Ícaro GusmÃo Pinto Vieira
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摘要: Objective : This study characterizeesters from carnauba crude powder and evaluates its hypoglycemic effect on the treatment of diabetic animals. Methods: Groups micewere induced by alloxan treated with powder. Blood samples were collected to determine glucose serum level. Results The compound was identified characterized as diester 4-methoxycinnamic acid (PCO-C) presented in concentrations 100 150 mg/kgbody weight (b.w. )The concentration mg/kg b.w..o.f PCO-C best controlling levels (p<0.05),when compared reference drug. Conclusion results indicate that is a promising therapeutic effect. action can be justified presence 4- methoxycinnamic acid.
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