Effects of Postshock Atrial Pacing on Atrial Defibrillation Outcome in the Isolated Sheep Heart
作者： A. C. Skanes , R. A. Gray , C. L. Zuur , J. Jalife
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摘要: Background—Failed atrial defibrillation shocks are associated with organization of postshock activity and a substantial electrical quiescence. We investigated the ability train pacing stimuli to capture or locally entrain myocardium during quiescent period after low-energy alter outcome. Methods Results—High-resolution video imaging near-defibrillation-threshold was performed in 12 Langendorff-perfused sheep hearts. A 10 (10-ms pulse width, 200-ms cycle length) coupled shock at various delays 7 Coupling intervals 40 130 ms were for feasibility first stimulus. The success rate 0, 0.08±0.08, 0.43±0.13, 0.73±0.13, 0.11±0.1 40-, 60-, 80-, 100-, 120-ms coupling intervals, respectively (P<0.001). In 5 experiments, interval fixed 100 (highest success, see above), stimulus amplitude ...
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