Up-converting reporters for biological and other assays using laser excitation techniques

作者: Gregory W. Faris , Mark J. Dyer , Michel J. Rossi , Norman A. Peppers , Steve Y. Ng

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摘要: The invention provides methods, compositions, and apparatus for performing sensitive detection of analytes, such as biological macromolecules other by labeling a probe molecule with an up-converting label. label absorbs radiation from illumination source emits at one or more higher frequencies, providing enhanced signal-to-noise ratio the essential elimination background sample autofluorescence. are suitable multiple analytes various clinical environmental sampling techniques.