Anesthetics or anesthetic techniques and cancer surgical outcomes: A possible link

摘要: As of 2018 cancer is responsible for almost 9.6 million deaths annually and, with an aging population, the incidence expected to continue rise. Surgery important treatment modality patients solid organ cancers. It has been postulated that, due potentially overlapping processes underlying development malignancy and therapeutic pathways various anesthetic agents, choice type method administration may affect post-operative outcomes in cancer. This a literature review most recent evidence extracted from databases including PubMed, EMBASE, Cochrane, as well journals book reference lists. The highlights pathophysiological underpinning molecular actions pre-clinical retrospective studies investigating anesthetics, ongoing clinical trials. Overall, there are conflicting results regarding impact regional vs. general anesthesia on recurrence, whilst majority data suggest benefit use intravenous propofol over inhalational volatile anesthetics. biological changes associated surgical inflammatory response offer unique opportunity intervene counteract any cancer-promoting effects.