What’s New in Pancreatic Stellate Cell Biology?

摘要: Fibrosis is a key pathological feature of chronic pancreatitis.1 It also major component the prominent desmoplastic (stromal) reaction observed around majority pancreatic cancers.2 now generally accepted that, far from being an inevitable end point injury, fibrosis active, dynamic process that reversible in its early stages. Therefore, understanding initial events fibrogenesis may allow identification novel therapeutic targets to prevent or retard progression.