Graft survival and effectiveness of dermal substitution in burns and reconstructive surgery in a one-stage grafting model.

摘要: Survival of the autograft and objective parameters for scar elasticity were evaluated after dermal substitution acute burns reconstructive surgery. The substitute, which was based on bovine type I collagen elastin-hydrolysate, by intraindividual comparison in a clinical trial. substitute applied one-step procedure combination with split-thickness autograft. This treatment compared conventional treatment, antograft. After 1 week, percentage survival assessed. Cutometer SEM 474 used to obtain measurements skin 3 4 months postoperatively. Forty-two pairs wounds (31 patients, age 32.9 +/- 19.3 years; burned surface area, 19.8 14.5 percent) treated because burns. Reconstructive surgery performed 44 33.9 17.5 years). Autograft not altered wounds, although slight but significant reduction (p = 0.015) established burn category substituted nonsubstituted wounds. However, necessity regrafting increased substitution. demonstrated increase pliability (50 percent, p < 0.001), (defined as immediate extension, 33 0.04), maximal extension (33 0.002), retraction 0.01), surgery, no improvement found different parameters. Dermal one-stage grafting model seems feasible respect graft survival. Skin considerably improved collagen/elastin