The natural history and epidemiology of venous thrombosis

摘要: Summary Epidemiologic studies over the past 30 years have provided much of basis for understanding venous thromboembolic disease. There has been an evolution from simple descriptive using clinical diagnosis to various forms comparative objective diagnoses. Identification high-risk cases in hospitalized population led development both general and specific antithrombotic prophylactic regimens. This occurred against a background increased pathophysiology thrombosis. Inhospital case interventions allowed direct questions concerning be addressed. Examples would include use certain types dosages anticoagulants mechanical devices avoid stasis. Despite these advances, there are still areas that require further attention. One aspect importance is evaluate thrombotic risk new procedures. The possibility procedure may either less or more than its predecessor should In former, additional measures needed. An example this relatively disappointing results regular low-dose heparin treatment some orthopedic latter, severe indicated. Current methods not without risks necessary with endoscopic surgical Another area relates monitoring compliance. information on available two decades, yet surveys application consistently show protocols used North America relative their equivalent institutions Europe. A third needs epidemiologic study incidence effects thrombosis community. recent cited above, little, as compared in-patient perspective, known about community factors prevention. With respect natural history hospital-based it seems unlikely gained surveying efficacy heparin-like mortality end points. However, large unsatisfactorily examined true frequency impact postphlebitic syndrome. germane hospital- community-acquired DVT and, aging population, clearly deserves lot