Conserved and divergent elements in Torso RTK activation in Drosophila development

作者: Marco Grillo , Marc Furriols , Cristina de Miguel , Xavier Franch-Marro , Jordi Casanova

DOI: 10.1038/SREP00762

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摘要: The repeated use of signalling pathways is a common phenomenon but little known about how they become co-opted in different contexts. Here we examined this issue by analysing the activation Drosophila Torso receptor embryogenesis and pupariation. While its putative ligand differs each case, show that Torso-like, not other proteins required for embryogenesis, also In addition, demonstrate distinct enhancers control torso-like expression both scenarios. We conclude linked to duplication differential ligand-encoding gene, acquisition promoter recruitment independently embryogenesis. A combination these mechanisms likely allow single

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