作者: Miles H. Sigler , , Brendan P. Teehan
DOI: 10.1038/KI.1987.245
关键词:
摘要: Solute transport in continuous hemodialysis: A new treatment for acute renal failure. pumpless dialysis technique which combines convection and diffusion was studied 15 critically ill failure patients. Fluid identical composition purity to that used peritoneal continuously circulated (single–pass) at 16.6 cc/min through the compartment of a 0.43 m 2 flat plate PAN membrane dialyzer. Whole blood clearances urea, creatinine phosphate averaged 25.3 ± 4.4 cc/min, 24.1 5.5 21.3 5.6 respectively. Over range flows (50 190 cc/min) these solutes were independent flow rate but rather determined by both dialysate ultrafiltration rate. In contrast net fluxes calcium sodium correlated only with Bicarbonate loss 0.52 0.11 mEq/min; K + balance varied ; glucose uptake from 107 24.0 mg/min. fresh non-clotting dialyzers, mean 8.1 cc/min. At Q Bi 70 solute equilibrate yielding total clearance equal outflow, or 25 is, sum plus comparison currently arteriovenous hemofiltration (CAVH), exceptionally–high obtained hemodialysis constitute significant improvement replacement therapy.