The effect of phenylpropanolamine on female stress urinary incontinence.

摘要: In a randomized double-blind manner, 43 women with grade I and II stress urinary incontinence were treated either phenylpropanolamine p.o. 50 mg twice daily (Rinexin, 1 tablet b.i.d.) or placebo during two weeks. Urethral CO2 profilometry, recording of maximum urethral closure pressure (MUCP) functional length (FUL), subjective response considered for effect evaluation. The Rinexin was highly significant (p = 0.01) above that placebo. Clinical improvement reported by 15 21 on 8 22 A increase in MUCP, 14%, registered treatment. This more pronounced the than incontinent women. No statistically correlations obtained between MUCP. An FUL recorded both treatment groups, but no difference them obtained. Adverse drug reactions rare. changes blood occurred. Based present study, (1 is an effective safe medication female also recommended as adjunctive therapy to physiotherapy before Teflon injection operation.