Bone marrow cell transplantation efficiently repairs tendon and ligament injuries.
作者： Taketoshi Kushida , Hirokazu Iida
关键词:
摘要: Growth factors such as transforming growth factor-β (TGF-β), vascular endothelial factor (VEGF), insulin-like factor-1 (IGF-1), platelet-derived (PDGF), and basic fibroblast (bFGF) have been associated with the tendon healing process (Molloy et al., 2003; Zhang Halper, 2014). Among these factors, TGF-β1 plays a key role during various tissue repair stages is secreted not only by fibroblasts differentiated from mesenchymal stem cells (MSCs), but also several types of that differentiate hematopoietic (HSCs; Sporn 1986). In this review, TGF-β MSC-derived in ligament described. Furthermore, potential application bone marrow cell transplantation (BMCT) novel method for treating injuries discussed.
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Raad Al-Shaikh, S. H. Liu, Rong-Sen Yang, J. M. Lane, Collagen in tendon, ligament, and bone healing. A current review. Clinical Orthopaedics and Related Research. pp. 265- 278 ,(1995)
Michael J. Mienaltowski, David E. Birk, Mouse Models in Tendon and Ligament Research Advances in Experimental Medicine and Biology. ,vol. 802, pp. 201- 230 ,(2014) , 10.1007/978-94-007-7893-1_13
Jaroslava Halper, Advances in the Use of Growth Factors for Treatment of Disorders of Soft Tissues Advances in Experimental Medicine and Biology. ,vol. 802, pp. 59- 76 ,(2014) , 10.1007/978-94-007-7893-1_5
Vinícius Y Moraes, Mário Lenza, Marcel Jun Tamaoki, Flávio Faloppa, João Carlos Belloti, None, Platelet rich therapies for musculoskeletal soft‐tissue injuries Cochrane Database of Systematic Reviews. ,vol. 2014, ,(2014) , 10.1002/14651858.CD010071.PUB3
D. Amiel, F. L. Harwood, W. H. Akeson, J. Lee, Growth factor expression in healing rabbit medial collateral and anterior cruciate ligaments. The Iowa orthopaedic journal. ,vol. 18, pp. 19- 25 ,(1998)
Xin Wang, Yu Wang, Wenlong Gou, Qiang Lu, Jiang Peng, Shibi Lu, Role of mesenchymal stem cells in bone regeneration and fracture repair: a review International Orthopaedics. ,vol. 37, pp. 2491- 2498 ,(2013) , 10.1007/S00264-013-2059-2
Atsushi Kanaya, Masataka Deie, Nobuo Adachi, Makoto Nishimori, Shinobu Yanada, Mitsuo Ochi, Intra-articular injection of mesenchymal stromal cells in partially torn anterior cruciate ligaments in a rat model. Arthroscopy. ,vol. 23, pp. 610- 617 ,(2007) , 10.1016/J.ARTHRO.2007.01.013
C. C. Schmidt, H. I. Georgescu, C. K. Kwoh, G. L. Blomstrom, C. P. Engle, L. A. Larkin, C. H. Evans, S. L-Y. Woo, Effect of growth factors on the proliferation of fibroblasts from the medial collateral and anterior cruciate ligaments Journal of Orthopaedic Research. ,vol. 13, pp. 184- 190 ,(1995) , 10.1002/JOR.1100130206
Elisabeth Ferreira, Ryan M. Porter, Nathalie Wehling, Regina P. O'Sullivan, Fangjun Liu, Adele Boskey, Daniel M. Estok, Mitchell B. Harris, Mark S. Vrahas, Christopher H. Evans, James W. Wells, Inflammatory cytokines induce a unique mineralizing phenotype in mesenchymal stem cells derived from human bone marrow. Journal of Biological Chemistry. ,vol. 288, pp. 29494- 29505 ,(2013) , 10.1074/JBC.M113.471268
Xiao Tian Wang, Paul Y. Liu, Jin Bo Tang, Tendon healing in vitro: Modification of tenocytes with exogenous vascular endothelial growth factor gene increases expression of transforming growth factor β but minimally affects expression of collagen genes The Journal of Hand Surgery. ,vol. 30, pp. 222- 229 ,(2005) , 10.1016/J.JHSA.2004.09.002