Oxidative stress, aging and longevity in Drosophila melanogaster.

摘要: Free radicals produced during normal metabolism cause damage to macromolecules. The free radical theory of aging proposes that the organism is unable repair all them and that, with time, unrepaired damages accumulate put at risk: in other words, provoke death. This article reviews both results adding antioxidants food on longevity Drosophila melanogaster, as well studies antioxidant enzymes (inactivation vivo, null mutants, overexpression). It concluded are probably poorly connected process, but they allow cope stressful conditions.