Urinary Bladder Matrix for the Treatment of Recalcitrant Nonhealing Radiation Wounds

摘要: Chronic wounds in previously radiated tissue are challenging to treat. In this article, the authors describe 3 such that failed heal despite multiple treatments with traditional wound healing methods. Treatment porcine urinary bladder matrix, an extracellular matrix material, was initiated facilitate epithelialization and promote healing. MatriStem powder (ACell, Inc, Columbia, Maryland), Inc) sheet, DuoDerm (ConvaTec, Skillman, New Jersey) were applied biweekly resulted complete closure within weeks of initial application for all cases. All remained closed 9 months following treatment, suggesting a role management chronic setting irradiated tissue.