Practical synthesis of all inositol stereoisomers from myo-inositol.
作者： Sung-Kee Chung , Yong-Uk Kwon
DOI: 10.1016/S0960-894X(99)00348-0
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摘要: Synthesis of six inositol stereoisomers was successfully carried out via conduritol intermediates prepared from myo-inositol. Dihydroxylation and epoxidation followed by ring opening the B, C F derivatives gave epi-, allo-, muco-, neo-, DL-chiro- scyllo-inositol. The cis-inositol derivative, which may not be this approach, synthesized in 5 steps 2-O-benzoyl-myo-inositol orthoformate as key intermediate.
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