Treatment of overactive bladder: what is on the horizon?

摘要: There is still a need to develop additional effective and well-tolerated therapies for the treatment of overactive bladder (OAB). The purpose this review discuss alternative idiopathic OAB that employ unique mechanism action or offer novel application an existing therapy. We performed comprehensive literature identify potential future treatments OAB. use botulinumtoxin on rise FDA approval will likely be granted in future. New innovations neuromodulation hold promise less invasive more patient-controlled therapies. A number medications, such as β-adrenoreceptor agonists, medications with indications, phosphodiesterase inhibitors, have been identified In addition, drug delivery systems, vaginal inserts, are also development may provide attractive deliver proven efficacy. While conservative measures behavioral modification pelvic floor exercises remain first-line therapy OAB, anti-muscarinics mainstay medical treatment. For patients refractory traditional therapies, promising new horizon.