Metastasizing atypical fibroxanthoma (cutaneous malignant histiocytoma): report of five cases.

作者: Jennifer Z. Cooper , Scott R. Newman , Glynis A. Scott , Marc D. Brown

DOI: 10.1111/J.1524-4725.2005.31046

关键词:

摘要: Background Atypical fibroxanthoma (AFX) is an unusual malignant fibrohistiocytic tumor of sun-damaged skin. When first described, it was felt to be a reactive low potential. More recently, has been shown intermediate potential. Objective To describe five cases metastatic AFX. Results Five patients ranging in age from 65 85 years old presented with AFX. Three the regional lymph node disease. Also, three had other aggressive cutaneous malignancies. LN-2 (CD74) staining positive primary tumors and two tumors. Conclusion The potential AFX may underestimated. useful marker identifying more behavior. JENNIFER Z. COOPER, MD, SCOTT R. NEWMAN, GLYNIS A. SCOTT, AND MARC D. BROWN, HAVE INDICATED NO SIGNIFICANT INTEREST WITH COMMERCIAL SUPPORTERS.

参考文章(22)
C. Doglioni, C. D. M. Fletcher, A. P. Dei Tos, D. Gasparotto, R. Maestro, L. Laurino, M. Boiocchi, Ultraviolet-induced p53 mutations in atypical fibroxanthoma. American Journal of Pathology. ,vol. 145, pp. 11- 17 ,(1994)
Philipp U Heitz, Angela Baer, Bruno Paredes, Daniela Mihic-Probst, Paul Komminoth, Parvin Saremaslani, Jianming Zhao, Christian Oehlschlegel, CGH analysis shows genetic similarities and differences in atypical fibroxanthoma and undifferentiated high grade pleomorphic sarcoma. Anticancer Research. ,vol. 24, pp. 19- 26 ,(2004) , 10.5167/UZH-111580
Ingvar Dahl, Atypical fibroxanthoma of the skin. A clinico-pathological study of 57 cases. Acta Pathologica Microbiologica Scandinavica Section A Pathology. ,vol. 84, pp. 183- 197 ,(2009) , 10.1111/J.1699-0463.1976.TB00088.X
Richard L. Kempson, Malcolm H. McGavran, Atypical fibroxanthomas of the skin Cancer. ,vol. 17, pp. 1463- 1471 ,(1964) , 10.1002/1097-0142(196411)17:11<1463::AID-CNCR2820171114>3.0.CO;2-E
F.H. Dilek, N. Akpolat, A. Metin, S. Ugras, Atypical fibroxanthoma of the skin and the lower lip in xeroderma pigmentosum. British Journal of Dermatology. ,vol. 143, pp. 618- 620 ,(2000) , 10.1111/J.1365-2133.2000.03721.X
David S. Jacobs, William D. Edwards, Richard C. Ye, Metastatic atypical fibroxanthoma of skin Cancer. ,vol. 35, pp. 457- 463 ,(1975) , 10.1002/1097-0142(197502)35:2<457::AID-CNCR2820350224>3.0.CO;2-3
N. Youssef, P. Vabres, T. Buisson, N. Brousse, S. Fraitag, Two unusual tumors in a patient with xeroderma pigmentosum: atypical fibroxanthoma and basosquamous carcinoma. Journal of Cutaneous Pathology. ,vol. 26, pp. 430- 435 ,(1999) , 10.1111/J.1600-0560.1999.TB01870.X
Megan J. Smith-Zagone, Victor G. Prieto, Ruth A. Hayes, Walter W. Timperman, A. Hafeez Diwan, HMB-45 (gp103) and MART-1 expression within giant cells in an atypical fibroxanthoma: a case report Journal of Cutaneous Pathology. ,vol. 31, pp. 284- 286 ,(2004) , 10.1111/J.0303-6987.2004.00173.X