Hypertension, Insulin Resistance, and Aldosterone: Sex-Specific Relationships
作者： Srividya Kidambi , Jane M. Kotchen , Shanthi Krishnaswami , Clarence E. Grim , Theodore A. Kotchen
DOI: 10.1111/J.1751-7176.2009.00084.X
关键词:
摘要: African Americans, particularly men, have the highest morbidity and mortality rates from hypertension in United States. The authors studied 527 Americans a general clinical research center to determine whether there are sex differences relationships between with insulin resistance (IR) aldosterone, which risk factors for cardiovascular disease. Measurements included ambulatory blood pressure (BP), anthropometric measures, plasma renin activity, aldosterone (PA) concentration, fasting serum lipids, glucose, insulin. IR was estimated using Homeostasis Model Assessment (HOMA) model. BP correlated both sexes. However, PA but not women. Compared men lower tertile of HOMA-IR, upper had higher mean systolic BP, odds ratio having hypertension, levels PA. association women, may contribute high prevalence disease American men.
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