The complexity of globus: a multidisciplinary perspective

摘要: Here, Nathalie Rommel, Jan Tack and colleagues provide an overview of the extensive literature concerning globus discuss quality evidence to date. They also put forward a potential theoretical model support management future research in globus. Globus is topic interest for many specialties including otorhinolaryngology, gastroenterology psychiatry/psychosomatic medicine, but, although hypotheses have been suggested, key questions about its aetiology remain. This Review provides this discusses has associated with oropharyngeal structural lesions, upper oesophageal sphincter disorders, GERD, psychosocial factors psychiatric comorbidity. However, findings are often contradictory remains highly inconclusive. Indeed, exception patients structural-based globus, Rome III criteria functional only apply subgroup idiopathic In clinical reality, there exists group who present (nonstructural) but nevertheless dysphagia, odynophagia or GERD—exclusion diagnosis according III. The symptomatology might be broader than previously thought. It therefore crucial approach not from one single perspective, multifactorial point view, focus on coexistence and/or interactions different mechanisms pathogenesis. could translated practice by adopting multidisciplinary method presenting