The role of oxidative stress in deoxynivalenol-induced DNA damage in HepG2 cells.

作者: Xiaoou Zhang , Liping Jiang , Chengyan Geng , Jun Cao , Laifu Zhong

DOI: 10.1016/J.TOXICON.2009.05.021

关键词:

摘要: … Deoxynivalenol (DON), also known as vomitoxin, is a type B … on Cancer (IARC), considered DON to be a Group 3 carcinogen, “not classifiable as to its carcinogenicity to humans” (IARC, …

参考文章(37)
F C Wehner, W F Marasas, P G Thiel, Lack of mutagenicity to Salmonella typhimurium of some Fusarium mycotoxins. Applied and Environmental Microbiology. ,vol. 35, pp. 659- 662 ,(1978) , 10.1128/AEM.35.4.659-662.1978
Regina M. Santella, Ta-Ming Hsu, Yu-Jing Zhang, Alicja Yarborough, Immunoperoxidase detection of 8-hydroxydeoxyguanosine in aflatoxin B1-treated rat liver and human oral mucosal cells. Cancer Research. ,vol. 56, pp. 683- 688 ,(1996)
Sylvie Bony, Monique Carcelen, Laurence Olivier, Alain Devaux, Genotoxicity assessment of deoxynivalenol in the Caco-2 cell line model using the Comet assay. Toxicology Letters. ,vol. 166, pp. 67- 76 ,(2006) , 10.1016/J.TOXLET.2006.04.010
T. Frankič, T. Pajk, V. Rezar, A. Levart, J. Salobir, The role of dietary nucleotides in reduction of DNA damage induced by T-2 toxin and deoxynivalenol in chicken leukocytes. Food and Chemical Toxicology. ,vol. 44, pp. 1838- 1844 ,(2006) , 10.1016/J.FCT.2006.06.002
Lambros Nousis, Paschalis-Thomas Doulias, Nektarios Aligiannis, Dimitrios Bazios, Apostolos Agalias, Dimitrios Galaris, Sofia Mitakou, DNA protecting and genotoxic effects of olive oil related components in cells exposed to hydrogen peroxide Free Radical Research. ,vol. 39, pp. 787- 795 ,(2005) , 10.1080/10715760500045806
H Sies, Oxidative stress: oxidants and antioxidants Experimental Physiology. ,vol. 82, pp. 291- 295 ,(1997) , 10.1113/EXPPHYSIOL.1997.SP004024
Daryl W. Fairbairn, Peggy L. Olive, Kim L. O'Neill, The comet assay: a comprehensive review Mutation Research\/reviews in Genetic Toxicology. ,vol. 339, pp. 37- 59 ,(1995) , 10.1016/0165-1110(94)00013-3
Saura C. Sahu, Larry H. Garthoff, Martin G. Robl, Stuart J. Chirtel, Dennis I. Ruggles, Thomas J. Flynn, Thomas J. Sobotka, Rat liver clone-9 cells in culture as a model for screening hepatotoxic potential of food-related products: hepatotoxicity of deoxynivalenol. Journal of Applied Toxicology. ,vol. 28, pp. 765- 772 ,(2008) , 10.1002/JAT.1337
Siegfried Knasmüller, Wolfram Parzefall, Ratna Sanyal, Sonja Ecker, Christina Schwab, Maria Uhl, Volker Mersch-Sundermann, Gary Williamson, Gerhard Hietsch, Theo Langer, Firouz Darroudi, Adayapalam T. Natarajan, Use of metabolically competent human hepatoma cells for the detection of mutagens and antimutagens Mutation Research. ,vol. 402, pp. 185- 202 ,(1998) , 10.1016/S0027-5107(97)00297-2