Evaluation of deoxynivalenol-induced toxic effects on DF-1 cells in vitro: Cell-cycle arrest, oxidative stress, and apoptosis

作者: Daotong Li , Yaqiong Ye , Shaoqing Lin , Li Deng , Xiaolong Fan

DOI: 10.1016/J.ETAP.2013.11.015

关键词: Cell cycle checkpointBiologyReactive oxygen speciesSuperoxide dismutaseOxidative stressCell cycleMalondialdehydeCell biologyViability assayApoptosis

摘要: … embryo fibroblast DF-1 cells. The results showed that DON significantly inhibited DF-1 cell … DON could also inhibit the proliferation of DF-1 cells through G2/M phase arrest in the cell …

参考文章(44)
Xiaoou Zhang, Liping Jiang, Chengyan Geng, Jun Cao, Laifu Zhong, None, The role of oxidative stress in deoxynivalenol-induced DNA damage in HepG2 cells. Toxicon. ,vol. 54, pp. 513- 518 ,(2009) , 10.1016/J.TOXICON.2009.05.021
James J. Pestka, Deoxynivalenol: Toxicity, mechanisms and animal health risks Animal Feed Science and Technology. ,vol. 137, pp. 283- 298 ,(2007) , 10.1016/J.ANIFEEDSCI.2007.06.006
Daliborka Dusanic, Dusan Bencina, Irena Oven, Ivanka Cizelj, Mojca Bencina, Mojca Narat, Mycoplasma synoviae induces upregulation of apoptotic genes, secretion of nitric oxide and appearance of an apoptotic phenotype in infected chicken chondrocytes Veterinary Research. ,vol. 43, pp. 7- 7 ,(2012) , 10.1186/1297-9716-43-7
James J. Pestka, Deoxynivalenol: mechanisms of action, human exposure, and toxicological relevance. Archives of Toxicology. ,vol. 84, pp. 663- 679 ,(2010) , 10.1007/S00204-010-0579-8
W. A. Awad, J. Bohm, E. Razzazi-Fazeli, J. Zentek, Effects of feeding deoxynivalenol contaminated wheat on growth performance, organ weights and histological parameters of the intestine of broiler chickens. Journal of Animal Physiology and Animal Nutrition. ,vol. 90, pp. 32- 37 ,(2006) , 10.1111/J.1439-0396.2005.00616.X
James H. Kouadio, Théophile A. Mobio, Isabelle Baudrimont, Serge Moukha, Sébastien D. Dano, E. Edmond Creppy, Comparative study of cytotoxicity and oxidative stress induced by deoxynivalenol, zearalenone or fumonisin B1 in human intestinal cell line Caco-2 Toxicology. ,vol. 213, pp. 56- 65 ,(2005) , 10.1016/J.TOX.2005.05.010
H.-Z. Lee, W.-Z. Liu, W.-T. Hsieh, F.-Y. Tang, J.-G. Chung, Henry W.-C. Leung, Oxidative stress involvement in Physalis angulata-induced apoptosis in human oral cancer cells Food and Chemical Toxicology. ,vol. 47, pp. 561- 570 ,(2009) , 10.1016/J.FCT.2008.12.013
Jingyun Wang, Pingping Sun, Yongming Bao, Jiwen Liu, Lijia An, Cytotoxicity of single-walled carbon nanotubes on PC12 cells. Toxicology in Vitro. ,vol. 25, pp. 242- 250 ,(2011) , 10.1016/J.TIV.2010.11.010