Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer

作者: Daniel Shiu-Hin Chan , Hui Yang , Maria Hiu-Tung Kwan , Zhen Cheng , Paul Lee

DOI: 10.1016/J.BIOCHI.2011.02.013

关键词:

摘要: … G-quadruplexes are non-canonical DNA secondary … c-myc oncogene G-quadruplex DNA. Based on molecular docking … for polymerase-drive DNA extension was examined using a PCR-…

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