Structure-based repurposing of FDA-approved drugs as TNF-α inhibitors.

作者: Chung-Hang Leung , Daniel Shiu-Hin Chan , Maria Hiu-Tung Kwan , Zhen Cheng , Chun-Yuen Wong

DOI: 10.1002/CMDC.201100016

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参考文章(27)
Michael A. Palladino, Frances Rena Bahjat, Emmanuel A. Theodorakis, Lyle L. Moldawer, Anti-TNF-α therapies: the next generation Nature Reviews Drug Discovery. ,vol. 2, pp. 736- 746 ,(2003) , 10.1038/NRD1175
Paul Abrams, Karl-Erik Andersson, Muscarinic receptor antagonists for overactive bladder BJU International. ,vol. 100, pp. 987- 1006 ,(2007) , 10.1111/J.1464-410X.2007.07205.X
Sybertz Ej, Alton Kb, Yumibe Np, Davis Hr, Compton Ds, Van Heek M, McLeod Rl, In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of the active metabolites of SCH48461. Journal of Pharmacology and Experimental Therapeutics. ,vol. 283, pp. 157- 163 ,(1997)
H Wajant, K Pfizenmaier, P Scheurich, Tumor necrosis factor signaling. Cell Death & Differentiation. ,vol. 10, pp. 45- 65 ,(2003) , 10.1038/SJ.CDD.4401189
Paul Abrams, Linda Cardozo, Magnus Fall, Derek Griffiths, Peter Rosier, Ulf Ulmsten, Philip Van Kerrebroeck, Arne Victor, Alan Wein, The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee of the International Continence Society Urology. ,vol. 61, pp. 37- 49 ,(2003) , 10.1016/S0090-4295(02)02243-4
Ronald J. Quinn, Anthony R. Carroll, Ngoc B. Pham, Paul Baron, Meredith E. Palframan, Lekha Suraweera, Gregory K. Pierens, Sorel Muresan, Developing a drug-like natural product library. Journal of Natural Products. ,vol. 71, pp. 464- 468 ,(2008) , 10.1021/NP070526Y
Jürgen Bajorath, Integration of virtual and high-throughput screening. Nature Reviews Drug Discovery. ,vol. 1, pp. 882- 894 ,(2002) , 10.1038/NRD941
I. D. Kuntz, Structure-based strategies for drug design and discovery. Science. ,vol. 257, pp. 1078- 1082 ,(1992) , 10.1126/SCIENCE.257.5073.1078
Chung-Hang Leung, Daniel Shiu-Hin Chan, Hui Yang, Ruben Abagyan, Simon Ming-Yuen Lee, Guo-Yuan Zhu, Wang-Fun Fong, Dik-Lung Ma, None, A natural product-like inhibitor of NEDD8-activating enzyme Chemical Communications. ,vol. 47, pp. 2511- 2513 ,(2011) , 10.1039/C0CC04927A
Shusuke Yagi, Masashi Akaike, Ken-ichi Aihara, Takashi Iwase, Kazue Ishikawa, Sumiko Yoshida, Yuka Sumitomo-Ueda, Kenya Kusunose, Toshiyuki Niki, Koji Yamaguchi, Kunihiko Koshiba, Yoichiro Hirata, Munkhbaatar Dagvasumberel, Yoshio Taketani, Noriko Tomita, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Toshio Matsumoto, Masataka Sata, Ezetimibe ameliorates metabolic disorders and microalbuminuria in patients with hypercholesterolemia. Journal of Atherosclerosis and Thrombosis. ,vol. 17, pp. 173- 180 ,(2010) , 10.5551/JAT.2378