Evaluation of gastric and bladder tonometry as indicators of tissue perfusion in induced hypotension in dogs.

摘要: Objective To evaluate the use of gastric (PgCO2) and bladder (PbCO2) tonometry for assessing tissue hypoperfusion in dogs during sevoflurane-induced hypotension, to compare these measurements with delivery oxygen, arterial oxygen content, plasma lactate concentration. Design Prospective experimental trial. Setting University veterinary teaching hospital. Animals Fourteen adult Beagle dogs. Interventions Anesthetic induction was performed by mask sevoflurane oxygen. Heart rate, direct pressures, respiratory end-tidal carbon dioxide were recorded; blood samples taken measure gases, venous sampled lactate. A tonometric catheter introduced into stomach PgCO2. Samples saline from balloon a Foley placed collected every 10 minutes used PbCO2 gas analysis. Tonometry measurements, lactate, consumption compared at 3 time points: baseline, treatment periods. hypotensive period (mean pressure (MAP) < 60 mm Hg) 15 induced an overdose sevoflurane, whereas period, constant-rate infusion dopamine (10 μg/kg/min) administered intravenously 40 minutes. Measurements Main Results Values PgCO2 increased significantly correlations found between values Gastric had stronger values. Conclusions Gastric can be detect hypoperfusion. Further studies are warranted determine potential clinical situations.