Diet and its role in interstitial cystitis/bladder pain syndrome (IC/BPS) and comorbid conditions

摘要: What's known on the subject? and What does study add? Nearly 90% of patients with interstitial cystitis/bladder pain syndrome (IC/BPS) report sensitivities to a wide variety dietary comestibles. Current questionnaire-based literature suggests that citrus fruits, tomatoes, vitamin C, artificial sweeteners, coffee, tea, carbonated alcoholic beverages, spicy foods tend exacerbate symptoms, while calcium glycerophosphate sodium bicarbonate improve symptoms. At present we recommend employing controlled method determine sensitivities, such as an elimination diet, in order identify at same time maintain optimal nutritional intake. We review current regard diet's effect upon IC/BPS common comorbidities (irritable bowel syndrome, fibromyalgia, chronic fatigue neuropathic pain, vulvodynia, headache) focus investigations. We discuss pathologic mechanisms may link diet related-pain, concentrating specific comestibles acidic foods, high potassium, caffeine, alcohol. • Up comestibles. • Pathological suggested be responsible for relationship between intake symptom exacerbation include peripheral and/or central neural upregulation, bladder epithelial dysfunction, organ ‘cross-talk’, amongst others. • Current data symptoms. • Specific comestible varied have been influenced by comorbid conditions. • This play important role patient management.